Feature:
Hydroxypropyl beta-cyclodextrinare purified polydisperse products resulting from the controlled reaction ofpropylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin isitself very soluble in water (greater than 500 mg/ml at room temperature comparedto 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a varietyof sparingly water compounds to enhance the aqueous solubility of theencapsulated compound.
CASNo.: 128446-35-5
MolecularFormula: C63H112O42
MolecularWeight: 1541.54
Specifications:
1. Appearance: White powder
2. Assay: ≥98%
3. Loss on Drying:≤4.5%
4. Chloride: ≤0.02%
5. Residue onIgnition: ≤1.5%
6. Heavy Metals:≤0.0025%
7. As: ≤0.0002%
8. Degree of substitution: 4-9
9. Total bacteria count: ≤1000 pcs/g
10. Moulds and yeasts:≤100 pcs/g
Application:
Pharmaceutical:
1. Suitable forparenteral use, syrups, solutions and oral suspensions as well as for dryformulations (with possibility of in-situ encapsulation).
2. To increasewater solubility of poorly soluble drugs.
3. To increasebioavailability.
4. To improveorganoleptic properties of bitter or unpleasant actives.
Cosmetics:
1. Suitable forencapsulation of volatile compounds.
2. To increaseshelf life of expensive flavours.