Hydroxypropyl-Beta-Cyclodextrin

Hydroxypropyl-Beta-Cyclodextrin

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Feature:

Hydroxypropyl beta-cyclodextrinare purified polydisperse products resulting from the controlled reaction ofpropylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin isitself very soluble in water (greater than 500 mg/ml at room temperature comparedto 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a varietyof sparingly water compounds to enhance the aqueous solubility of theencapsulated compound.

CASNo.:  128446-35-5

MolecularFormula:    C63H112O42

MolecularWeight:     1541.54

Specifications

1. Appearance: White powder

2. Assay: ≥98%

3. Loss on Drying:≤4.5%

4. Chloride: ≤0.02%

5. Residue onIgnition: ≤1.5%

6. Heavy Metals:≤0.0025%

7. As: ≤0.0002%

8. Degree of substitution: 4-9

9. Total bacteria count: ≤1000 pcs/g

10. Moulds and yeasts:≤100 pcs/g

Application:

Pharmaceutical:

1. Suitable forparenteral use, syrups, solutions and oral suspensions as well as for dryformulations (with possibility of in-situ encapsulation).

2. To increasewater solubility of poorly soluble drugs.

3. To increasebioavailability.

4. To improveorganoleptic properties of bitter or unpleasant actives.

Cosmetics:

1. Suitable forencapsulation of volatile compounds.

2. To increaseshelf life of expensive flavours.